Archive for the ‘biomedical research’ Category



When Shooting at the Moon, Take Careful Aim Before Firing

February 23rd, 2016
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During his final State of the Union address, President Obama announced he is charging Vice President Biden with leading a new “moonshot” program to accelerate the pace of improvements in cancer care. While the goal is certainly laudable, I share the “sense of déjà vu” that was eloquently expressed by Vinay Prasad in his recent editorial1 in which he recounts the limited progress seen in the Nixon-era War on Cancer, and even more recently in the G.W. Bush era, when then-NCI Director Andrew Van Eschenbach testified that we could rid the world of cancer by 2010 for just $600 million per year.
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Single Cell Biology: A Step Toward Precision Diagnostics

January 21st, 2016
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The past several years have seen a dramatic increase in the ability to isolate and characterize single cells – leading to advances in diagnostics, drug discovery, stem cell biology, cancer, and many other areas of biomedical research.

These advances have arisen thanks to growing capabilities in various single cell “omics” technologies – which have enabled RNA and DNA sequencing on a genome-wide scale (the interrogation of proteins, metabolites, and many other types of molecules that provide information about cellular growth, differentiation, and the underlying molecular basis of disease).

And why has single cell technology become so attractive within the biomedical research community? Because most studies are currently hampered by sample heterogeneity.

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